Hydrodiuril, the brand name for the drug hydrochlorothiazide, has a primary role of a diuretic or water pill and its major functionality is to block salt and fluid reabsorption in the kidneys in order to cause increased and more frequent urination or diuresis. The drug is also used t treat excessive swelling or edema as caused by cirrhosis, heart failure, and chronic kidney failure. A lesser-known use for hydrochlorothiazide is to treat mildly high blood pressure. Hydrochlorothiazide is available through dispensing of a prescription tablet for either 25 mg, 50 mg, or 100 mg and there are generic options available to patients and this medication can be taken on an empty stomach if that is desired. Hydrochlorothiazide should be stored at room temperature in a light-resistant and tamper proof bottle that is clearly labeled and out of the reach of children.
Hydrochlorothiazide, though seemingly harmless, does reportedly have some serious drug interactions. As discussed above, patients on dialysis and with liver disease should only take this medication under the supervision of a doctor because of fluid and electrolyte problems in association with the disease. The chemical structure of sulfa is very similar to that of Hydrochlorothiazide so those who are allergic to sulfa should also stay away from Hydrochlorothiazide. Blood uric acid levels can experience increases during treatment with a rare occurrence of gout. Hydrochlorothiazide also reduces the kidney excretion of lithium due to the rapid flushing of the kidneys and can result in lithium toxicity. There have been no safe uses identified for pregnant women and children since the creation of this medication. Periodic blood tests are performed to monitor kidney function and electrolytes during treatment with hydrochlorothiazide
Hydrochlorothiazide is most commonly associated with side effects that include weakness, low blood pressure, rash, light sensitivity, impotence, nausea, abdominal pain, electrolyte disturbances, pancreatitis, jaundice, anaphylaxis, and severe rashes.
Disclaimer: Cliff Schaffer does not personally endorse or support any of the comments made within the writings of this article.