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American Society for Action on Pain

UI - 000031

AU - Millan MJ

AU - Millan MH

AU - Czlonkowski A

AU - Pilcher CWT

AU - Hollt V

AU - Colpaert FC

AU - Herz A

TI - Functional response of multiple opioid systems to chronic arthritic pain in the rat

ED -

BK - Stress-induced analgesia. Annals of the New York Academy of Sciences, Vol. 467. (Dennis D. Kelly,

Ed.), pp. 182-193. New York Academy of Sciences, New York, NY, US; 449 pp.<<SEE BOOK>>


Max-Planck-Inst fur Psychiatrie LA: English SP: Sponsor; Deutsche Forschungsgemeinschaft, Bonn,

Federal Republic of Germany CR: (from the chapter) there is ...a multiplicity of opioid ligands and opioid

receptors that display a differential distribution and modulation and appear to subserve contrasting functional

roles / in addition, there are many independently localized pools of the respective opioid peptides and opioid

receptors / consequently, the often-formulated question as to the role of opioid systems in pain control may

be a misleading oversimplification / it is necessary to examine these questions within the perspective of the

multiplicity of these opioid systems /// summarizes the findings of our recent work in which such an

approach was adopted for an evaluation of the functional response of particular opioid systems to a model of

chronic pain in the rat--adjuvant-induced arthritis

SO - New York, NY, US ,New York Academy of Sciences 1986;:182-193